Gene Expression Data
Assay Details
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Assay
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Reference:
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J:162095
Shiwaku H, et al., Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO J. 2010 Jul 21;29(14):2446-60
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5638229
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Gene symbol:
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Slc1a3
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Gene name:
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solute carrier family 1 (glial high affinity glutamate transporter), member 3
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Antibody:
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Anti-Glast
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Detection system:
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Secondary antibody
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Results
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Specimen
6D WT:
postnatal week 1
(more  )
Specimen
6D WT:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebellum |
Present |
Regionally restricted |
6D WT Glast
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Expression was detected in Bergmann glia.
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Specimen
6D Atx1-KI:
postnatal week 1; Atxn1tm1Hzo/Atxn1 +
(more )
Specimen
6D Atx1-KI:
(close )
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Genetic Background:
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B6.129S7-Atxn1tm1Hzo
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Mutant Allele(s):
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Atxn1tm1Hzo/Atxn1+
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Age:
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postnatal week 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebellum |
Weak |
Regionally restricted |
6D Atx1-KI Glast
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The number of Bergmann glia was reduced. Expression in Bergmann glia cells was also reduced in the mutant.
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Analysis Tools