Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sox7tm1.1Nat
Name:	SRY (sex determining region Y)-box 7; targeted mutation 1.1, Jeremy Nathans
MGI ID:	MGI:5638074
Synonyms:	Sox7fl, Sox7flox
Gene:	Sox7  Location: Chr14:64181155-64188181 bp, + strand  Genetic Position: Chr14, 33.34 cM, cytoband C3
Alliance:	Sox7tm1.1Nat page

Germline Transmission:	Earliest citation of germline transmission: J:264733
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: LoxP sites are inserted (1) within the first exon 5' of the initiator methionine codon, and (2) 3' of an SV40 polyadenylation signal that is inserted immediately 3' of the 3' UTR. Inserted downstream of the 3' loxP site are the coding region for CFP with a 3' HA tag, an FRT site, a phosphoglycerate kinase (PGK)-Neo cassette, a third loxP site and an FRT site. (J:264733)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	24 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox7 Mutation:	21 strains or lines available

Original:	J:264733 Zhou Y, et al., Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina. PLoS One. 2015;10(12):e0143650
All:	4 reference(s)