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Gene Expression Data
Assay Details
Assay
Reference: J:72548 Brachtendorf G, et al., Early expression of endomucin on endothelium of the mouse embryo and on putative hematopoietic clusters in the dorsal aorta. Dev Dyn. 2001 Nov;222(3):410-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5637528
Gene symbol: Emcn
Gene name: endomucin
Antibody: V.5C7
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The authors developed three monoclonal antibodies but did not specify which was used to generate the data in Figs 3 and 5; it is possible V.1A7 (MGI:5637518) or even V.7C7 (MGI:5637519) was used to generate those data.
Results
Specimen 3A embryo: embryonic day 7.0 (more )
Note: transverse section
Structure Level Pattern Image Note
TS10: embryo Absent 3A

Specimen 3A mother: postnatal adult (more )
Note: transverse section
Structure Level Pattern Image Note
TS28: vasculature of uterus Present 3A Expression is present in the blood vessels of the utuerus.

Specimen 3D: embryonic day 8.0 (more )
Note: parasagittal section
Structure Level Pattern Image Note
TS12: blood vessel Strong 3D Expression is present in intersomitic vessels.

Specimen 3G/H/I: embryonic day 8.0 (more )
Note: transverse section
Structure Level Pattern Image Note
TS12: blood vessel Present 3I , 3G , 3H
TS12: blood island Absent 3G , 3H , 3I

Specimen 3G mother: postnatal adult (more )
Note: transverse section
Structure Level Pattern Image Note
TS28: vasculature of uterus Present 3G Expression is present in the blood vessels of the utuerus.

Specimen 3K: embryonic day 8.5-9.0 (more )
Note: parasagittal section
Structure Level Pattern Image Note
TS13: blood vessel Present 3K Expression is present in the endothelium of capillaries and large blood vessels throughout the embryo.

Specimen 4A/B/C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal aorta Strong Clusters 4C , 4A , 4B Expression is present on the endothelium of the aorta, as well as on cell clusters associated with the endothelium; they may be hmatopoietic progenitors.

Specimen 4L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: blood vessel Present 4L Expression is present in venules.
TS23: blood Present 4L The stained cell could be either a circulating endothelial precursor or a hematopoietic progenitor.

Specimen 5A/D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: renal vasculature Present 5A
TS23: descending aorta Present 5D , 5A Focal expression is observed.
TS23: epithelium Absent 5A

Specimen 5G: postnatal adult (more )
Note: transverse section
Structure Level Pattern Image Note
TS28: aorta Present 5G Focal expression is observed.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory