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Gene Expression Data
Assay Details
Assay
Reference: J:47697 Jain S, et al., Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. Mech Dev. 1998 Apr;73(1):117-23
Assay type: RNA in situ
MGI Accession ID: MGI:5637330
Gene symbol: Epas1
Gene name: endothelial PAS domain protein 1
Probe: Hif2a cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood vessel Strong 1_HIF2 alpha
TS15: cardiovascular system Strong 1_HIF2 alpha
TS15: dorsal aorta Strong 1_HIF2 alpha
TS15: urogenital ridge Strong 1_HIF2 alpha
TS15: chorionic plate Strong Regionally restricted 1_HIF2 alpha Expression was extremely high in the chorionic villi.
TS28: placenta Strong Regionally restricted 1_HIF2 alpha Expression was extremely high in the decidual cells of the placenta.

Specimen 2: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: blood vessel Present Uniform 2_HIF2 alpha Expression was uniform in the endothelium.
TS21: choroid plexus Present Uniform 2_HIF2 alpha Expression was uniform in the endothelium.
TS21: dorsal aorta Present Uniform 2_HIF2 alpha Expression was uniform in the endothelium.
TS21: brain vascular element Present Regionally restricted 2_HIF2 alpha Expression was in the sprouting capillaries in the brain.
TS21: lung mesenchyme Present 2_HIF2 alpha
TS21: metanephros Present 2_HIF2 alpha
TS21: urogenital ridge Present 2_HIF2 alpha

Specimen 3A: embryonic day 15.5 (more )
Note: Section of the head.
Structure Level Pattern Image Note
TS23: olfactory epithelium Present 3A HIF2 alpha
TS23: head Present 3A HIF2 alpha The expression pattern of E13.5 continued to be displayed at E15.5.

Specimen 3B: embryonic day 15.5 (more )
Note: Section of the trunk.
Structure Level Pattern Image Note
TS23: adrenal gland Present 3B HIF2 alpha
TS23: brown fat Present 3B HIF2 alpha
TS23: cardiovascular system Present 3B HIF2 alpha
TS23: trunk Present 3B HIF2 alpha The expression pattern of E13.5 continued to be displayed at E15.5.

Specimen 4 bladder: postnatal adult (more )
Structure Level Pattern Image Note
TS28: vasculature of bladder Present Regionally restricted 4_HIF2 alpha bladder Expression was detected in the capillaries of the connective tissue underlying the transitional epithelium.

Specimen 4 testes: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: seminiferous tubule epithelium Present Regionally restricted 4_HIF2 alpha testes Expression was detected in the primary gonocytes.
TS28: Leydig cell Leydig cell Present 4_HIF2 alpha testes

Specimen 4 YS: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac Present 4_HIF2 alpha YS


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory