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Gene Expression Data
Assay Details
Assay
Reference: J:65443 Eib DW, et al., Expression of the follistatin/EGF-containing transmembrane protein M7365 (tomoregulin-1) during mouse development. Mech Dev. 2000 Oct;97(1-2):167-71
Assay type: RNA in situ
MGI Accession ID: MGI:5636716
Gene symbol: Tmeff1
Gene name: transmembrane protein with EGF-like and two follistatin-like domains 1
Probe: M7365
Probe preparation: Antisense RNA
Results
Specimen 2a: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: 1st branchial arch Strong 2a
TS13: somite Strong 2a
TS13: lateral plate mesoderm Strong Regionally restricted 2a Expression is in splanchnic mesoderm.
TS13: foregut diverticulum Strong Regionally restricted 2a Expression is in the ventral foregut epithelium.
TS13: embryo Weak 2a Low expression in other tissues.

Specimen 2b: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube lateral wall Strong Regionally restricted 2b Expression is in motor and superficial neurons.
TS15: diencephalon Strong Regionally restricted 2b Expression is dorsal.
TS15: future midbrain Strong Regionally restricted 2b Expression is dorsal.

Specimen 3a: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: thalamus Strong Regionally restricted 3a Expression is in the lateral thalamic nucleus.
TS23: cerebral cortex Strong 3a
TS23: hippocampus Strong 3a
TS23: inferior colliculus Strong 3a
TS23: cerebellum Strong Regionally restricted 3a Expression is in the fastigial nucleus of the cerebellum.
TS23: medulla oblongata Strong Regionally restricted 3a
TS23: autonomic ganglion Present Regionally restricted 3a Expression is in ganglia in the lung, stomach, intestine, abdominal aorta, and the heart.
TS23: liver Absent
TS23: metanephros Absent
TS23: skeletal muscle Absent

Specimen 3b: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Strong 3b
TS23: cerebellum Strong Regionally restricted 3b Expression is in the fastigial nucleus of the cerebellum.
TS23: thalamus Strong Regionally restricted 3b Expression is in the lateral thalamic nucleus.
TS23: brain Weak Regionally restricted 3b

Specimen 3c: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: medulla oblongata Strong 3c
TS23: spinal cord Strong 3c
TS23: cochlear ganglion Present 3c
TS23: trigeminal ganglion Present 3c
TS23: brain Weak Regionally restricted 3c

Specimen 3d: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: superior cervical ganglion Strong 3d
TS23: neural retina Present 3d
TS23: trigeminal ganglion Present 3d
TS23: brain Weak Regionally restricted 3d

Specimen 3e: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord Strong 3e
TS23: dorsal root ganglion Present 3e
TS23: sympathetic ganglion Present 3e
TS23: autonomic ganglion Present Regionally restricted 3e Expression is in ganglia of the prostatic region of the urethra.
TS23: brain Weak Regionally restricted 3e

Specimen 5a: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: lateral preoptic area Present 5a
TS28: medial preoptic nucleus Present 5a
TS28: supraoptic nucleus Present 5a

Specimen 5b: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: adenohypophysis pars anterior Very strong Regionally restricted 5b Expression is in the dorsal-lateral periphery.
TS28: adenohypophysis pars intermedia Weak Regionally restricted 5b Weaker signals at the extreme ventral positions.
TS28: median eminence Present 5b
TS28: neurohypophysis pars nervosa Absent 5b

Specimen 5c: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Strong 5c

Specimen 5d: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 5d
TS28: cerebellum granule cell layer Strong 5d

Specimen 5e: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: locus coeruleus Strong 5e
TS28: brainstem nucleus Strong 5e Expression is in the sub coeruleus.

Specimen 5f: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Very strong 5f
TS28: hippocampus CA2 Very strong 5f
TS28: hippocampus CA3 Very strong 5f
TS28: hippocampus CA4 Very strong 5f
TS28: dentate gyrus Present 5f
TS28: hippocampus Present 5f

Specimen not shown: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: hypothalamic nucleus Present Regionally restricted Expression is in the magnocellular preoptic nuclei.
TS28: cingulate cortex Present
TS28: piriform cortex Present
TS28: primary motor cortex Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory