Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Kcnq2tm1.1Chkg
Name:	potassium voltage-gated channel, subfamily Q, member 2; targeted mutation 1.1, Chih H King
MGI ID:	MGI:5636592
Synonyms:	Kcnq2fl
Gene:	Kcnq2  Location: Chr2:180717372-180777093 bp, - strand  Genetic Position: Chr2, 103.57 cM, cytoband H3-4
Alliance:	Kcnq2tm1.1Chkg page

Germline Transmission:	Earliest citation of germline transmission: J:215353
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exons 3 through 5 floxed. (J:215353)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnq2 Mutation:	47 strains or lines available

Original:	J:215353 King CH, et al., Kv7.2 regulates the function of peripheral sensory neurons. J Comp Neurol. 2014 Oct 1;522(14):3262-80
All:	1 reference(s)