Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Aldh1l1tm1(cre)Pfw
Name:	aldehyde dehydrogenase 1 family, member L1; targeted mutation 1, Paul Worley
MGI ID:	MGI:5635921
Gene:	Aldh1l1  Location: Chr6:90527751-90576153 bp, + strand  Genetic Position: Chr6, 40.16 cM
Alliance:	Aldh1l1tm1(cre)Pfw page

Germline Transmission:	Earliest citation of germline transmission: J:217386
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Recombinase, Reporter) Mutation:    Insertion   Aldh1l1tm1(cre)Pfw expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Aldh1l1 (MGI:1340024)   Mutation details: An EGFP-cre cDNA was inserted right after the promoter. The insertion disrupts the reading frame. Western blot analysis confirmed the absence of protein in the brain. (J:217386)

Activity:	Tissue activity of this recombinase allele
Driver:	Aldh1l1 (mouse) Summary of all recombinase alleles driven by Aldh1l1. Alliance mouse Aldh1l1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aldh1l1 Mutation:	58 strains or lines available

Original:	J:217386 Zou Y, et al., Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain. J Neurosci. 2014 Nov 19;34(47):15764-78
All:	1 reference(s)