Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Opalintm1(cre)Pfw
Name:	oligodendrocytic myelin paranodal and inner loop protein; targeted mutation 1, Paul Worley
MGI ID:	MGI:5635920
Synonyms:	Tmem10-Cre
Gene:	Opalin  Location: Chr19:41050398-41065552 bp, - strand  Genetic Position: Chr19, 34.36 cM
Alliance:	Opalintm1(cre)Pfw page

Germline Transmission:	Earliest citation of germline transmission: J:217386
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Recombinase) Mutation:    Insertion   Opalintm1(cre)Pfw expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Opalin (MGI:2657025)     The cre cDNA was inserted into the open reading frame. (J:217386)

Activity:	Tissue activity of this recombinase allele
Driver:	Opalin (mouse) Summary of all recombinase alleles driven by Opalin. Comparative matrix view of recombinase activities Alliance mouse Opalin gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Opalin Mutation:	9 strains or lines available

Original:	J:217386 Zou Y, et al., Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain. J Neurosci. 2014 Nov 19;34(47):15764-78
All:	2 reference(s)