Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Rrp8tm1Jyan
Name:	ribosomal RNA processing 8; targeted mutation 1, Junn Yanagisawa
MGI ID:	MGI:5635913
Synonyms:	NML-
Gene:	Rrp8  Location: Chr7:105380937-105386592 bp, - strand  Genetic Position: Chr7, 55.97 cM
Alliance:	Rrp8tm1Jyan page

Germline Transmission:	Earliest citation of germline transmission: J:211809
Parent Cell Line:	iTL BA1 (ES Cell)
Strain of Origin:	(C57BL/6NTac x 129S6/SvEvTac)F1

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 2-5 were replaced with neomycin cassette that was subsequently removed via Cre-mediated recombination. Southern blot analysis confirmed the exons deletion. (J:211809)

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rrp8 Mutation:	25 strains or lines available

Original:	J:211809 Oie S, et al., Hepatic rRNA transcription regulates high-fat-diet-induced obesity. Cell Rep. 2014 May 8;7(3):807-20
All:	2 reference(s)