Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Stx1btm1Tfuj
Name:	syntaxin 1B; targeted mutation 1, Tomonori Fujiwara
MGI ID:	MGI:5635790
Synonyms:	Stx1btm1Tkof
Gene:	Stx1b  Location: Chr7:127403072-127423703 bp, - strand  Genetic Position: Chr7, 69.75 cM
Alliance:	Stx1btm1Tfuj page

Germline Transmission:	Earliest citation of germline transmission: J:214691
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exon 9 and 10, which encode the H3 and transmembrane domains. Western blot analysis confirmed the absence of protein expression in the brain. (J:214691)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stx1b Mutation:	21 strains or lines available

Original:	J:214691 Kofuji T, et al., HPC-1/syntaxin 1A and syntaxin 1B play distinct roles in neuronal survival. J Neurochem. 2014 Aug;130(4):514-25
All:	3 reference(s)