Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Serpina3ntm1.1Lbrl
Name:	serine (or cysteine) peptidase inhibitor, clade A, member 3N; targeted mutation 1.1, Stephen Liberles
MGI ID:	MGI:5635495
Synonyms:	Serpina3nfl
Gene:	Serpina3n  Location: Chr12:104372988-104380588 bp, + strand  Genetic Position: Chr12, 54.17 cM, cytoband F1
Alliance:	Serpina3ntm1.1Lbrl page

Germline Transmission:	Earliest citation of germline transmission: J:220590
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 2, and a frt-flanked neomycin resistance (neo) cassette followed by a second loxP site downstream of exon 2. Flp-mediated recombination removed the selection cassette. (J:220590)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Serpina3n Mutation:	30 strains or lines available

Original:	J:220590 Vicuna L, et al., The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015 May;21(5):518-23
All:	1 reference(s)