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Gene Expression Data
Assay Details
Assay
Reference: J:78589 Tarabykin V, et al., Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression. Development. 2001 Jun;128(11):1983-93
Assay type: RNA in situ
MGI Accession ID: MGI:5635120
Gene symbol: Otx1
Gene name: orthodenticle homeobox 1
Probe: Otx1 probe10
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present 1D

Specimen 1G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present 1G
TS21: cerebral cortex subventricular zone Absent 1G

Specimen 1J: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present 1J
TS21: cerebral cortex subventricular zone Absent 1J

Specimen 1M: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Moderate 1M
TS23: cerebral cortex ventricular layer Moderate 1M
TS23: cortical plate Moderate 1M

Specimen 1P: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Moderate 1P
TS23: cerebral cortex ventricular layer Moderate 1P
TS23: cortical plate Moderate 1P

Specimen 2A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cortical plate Present Regionally restricted 2A Prominent expression in lower part of cortical plate.
TS26: cerebral cortex intermediate zone Present Regionally restricted 2A Expression in some cells migrating through intermediate zone
TS26: cerebral cortex ventricular zone Weak 2A Reduced expression in the ventricular zone

Specimen 2D: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cortical layer V Present Regionally restricted 2D Expression in some neurons in layers V-VI.
TS27: cortical layer VI Present Regionally restricted 2D Expression in some neurons in layers V-VI.

Specimen 6A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present 6A

Specimen 6D: embryonic day 15.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present 6D Expression in the ventricular zone was not affected in mutant embryos compared with wild-type.

Specimen 6G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Present 6G
TS26: cortical plate Present 6G

Specimen 6J: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Present 6J Expression in the ventricular zone of the cortical plate was of comparable size in mutant and wild-type brains.
TS26: cortical plate Present Regionally restricted 6J Authors report there wer almost no cells in the outermost expression domain of the cortical plate.

Specimen 7A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: frontal cortex Present 7A

Specimen 7D: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: frontal cortex Present 7D No differences in expression along the A-P axis

Specimen 7G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: occipital cortex Present 7G

Specimen 7J: embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: occipital cortex Present 7J


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory