Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Cyp1a1tm1.1(cre)Arte
Name:	cytochrome P450, family 1, subfamily a, polypeptide 1; targeted mutation 1.1, TaconicArtemis
MGI ID:	MGI:5635035
Synonyms:	CreCyp1a1-KI
Gene:	Cyp1a1  Location: Chr9:57595211-57611107 bp, + strand  Genetic Position: Chr9, 31.34 cM
Alliance:	Cyp1a1tm1.1(cre)Arte page

Germline Transmission:	Earliest citation of germline transmission: J:218526
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Null/knockout, Recombinase) Mutations:    Insertion, Intragenic deletion   Cyp1a1tm1.1(cre)Arte expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Cyp1a1 (MGI:88588)   Mutation details: The coding sequence was replaced with a cre recombinse gene and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:218526)

Activity:	Tissue activity of this recombinase allele
Driver:	Cyp1a1 (mouse) Summary of all recombinase alleles driven by Cyp1a1. Alliance mouse Cyp1a1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyp1a1 Mutation:	38 strains or lines available

Original:	J:218526 Henderson CJ, et al., Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability. Biochem J. 2015 Feb 1;465(3):479-88
All:	4 reference(s)