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Gene Expression Data
Assay Details
Assay
Reference: J:184087 Sugiyama M, et al., Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development. Int Immunol. 2012 Jun;24(6):369-78
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5634452
Gene symbol: Tnfsf11
Gene name: tumor necrosis factor (ligand) superfamily, member 11
Antibody: anti-RANKL (IK22/5)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lymphatic system Present Regionally restricted 2A Expression is in the para-aortic mesenteric lymph node anlagen.
Specimen 2D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hemolymphoid system Present Regionally restricted 2D Expression is in central part of the para-aortic mesenteric lymph node anlagen in lymphoid tissue inducer cells and in mesenchyme.
Specimen 4A: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: lymphatic system Present Regionally restricted 4A Expression is in the mesenchyme in the mesenteric lymph node.
Specimen 4B: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: lymphatic system Present Regionally restricted 4B Expression is in the mesenchyme in the mesenteric lymph node.
Specimen 4C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lymph node Present Regionally restricted 4C Expression is in the mesenchyme in a side of sinus capsule connecting to afferent lymph vessel of the mesenteric lymph node.
Specimen 4D: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: Peyer's patch Present 4D
Specimen 4E: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: Peyer's patch Present Regionally restricted 4E Expression is in subepithelial dome region mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory