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Tg(Pmch-tTA)BAhky
Transgene Detail
Summary
Symbol: Tg(Pmch-tTA)BAhky
Name: transgene insertion B, Akihiro Yamanaka
MGI ID: MGI:5634283
Synonyms: MCH-tTA
Transgene: Tg(Pmch-tTA)BAhky  Location: unknown  
Alliance: Tg(Pmch-tTA)BAhky page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsA mammalianized tetracycline-controlled transactivator (tTA) was inserted into the mouse BAC RP23-348H6 at the translation initiation site of Pmch. Two founders were created, line B was used. (J:211265)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:211265 Tsunematsu T, et al., Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation. J Neurosci. 2014 May 14;34(20):6896-909
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory