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Hamptm1Ddhf
Targeted Allele Detail
Summary
Symbol: Hamptm1Ddhf
Name: hepcidin antimicrobial peptide; targeted mutation 1, Duygu Dee Harrison-Findik
MGI ID: MGI:5634088
Synonyms: Hamp1flx
Gene: Hamp  Location: Chr7:30641793-30643454 bp, - strand  Genetic Position: Chr7, 19.27 cM
Alliance: Hamptm1Ddhf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:220227
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: The targeting vector contains a FRT-flanked PGK-neomycin selection cassette and a 3' loxP site and is inserted downstream of exon 3, and another loxP site is inserted upstream of exon 2. (J:220227)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Hamp Mutation:  16 strains or lines available
References
Original:  J:220227 Lu S, et al., Inductively coupled mass spectrometry analysis of biometals in conditional Hamp1 and Hamp1 and Hamp2 transgenic mouse models. Transgenic Res. 2015 Aug;24(4):765-73
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory