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Gene Expression Data
Assay Details
Assay
Reference: J:47968 Wertz K, et al., Dmd(mdx-beta geo): a new allele for the mouse dystrophin gene. Dev Dyn. 1998 Jun;212(2):229-41
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5633943
Gene symbol: Dmd
Gene name: dystrophin, muscular dystrophy
Reporter: lacZ
Direct Detection
Results
Specimen 4A: embryonic day 8.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 4A Expression in neural plate caudal to the developing hindbrain.
Specimen 4B: embryonic day 9.0; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS14: future telencephalon Strong 4B
TS14: somite Present Regionally restricted 4B Expression in lateral somite, greater in posterior part of each segment.
Specimen 4C: embryonic day 9.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS15: future hindbrain floor plate Present 4C
TS15: future hindbrain roof plate Present 4C
TS15: optic vesicle Present 4C
TS15: heart Weak Regionally restricted 4C Weak expression in region around the developing atrioventricular valves.
Specimen 4D: embryonic day 9.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS15: future hindbrain floor plate Present 4D
TS15: future hindbrain roof plate Present 4D
TS15: optic vesicle Present 4D
Specimen 4E: embryonic day 10.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS17: somite Present Regionally restricted 4E Expression in lateral somite, greater in posterior part of each segment.
TS17: limb mesenchyme Present Regionally restricted 4E Expression in scattered cells in dorsal mesenchyme.
TS17: blood vessel Present Regionally restricted 4E Expression in endothelium of large caliber blood vessels.
Specimen 4F: embryonic day 10.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS17: lens pit Present 4F
TS17: optic cup Present Regionally restricted 4F Expression in retina.
TS17: inner ear Present 4F
Specimen 4G: embryonic day 10.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS17: visceral pericardium Present 4G Expression in epicardium.
TS17: heart septum Present Regionally restricted 4G Expression in ventricular septum.
Specimen 4H: embryonic day 10.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS17: brain floor plate Present Regionally restricted 4H Floor plate expression in a striped pattern.
Specimen 4I: embryonic day 10.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS17: somite Present Regionally restricted 4I Expression in lateral somite, greater in posterior part of each segment.
Specimen 4J: embryonic day 10.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS17: somite Present Regionally restricted 4J Expression in lateral somite, greater in posterior part of each segment.
Specimen 4K: embryonic day 10.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS17: somite Present Regionally restricted 4K Expression in lateral somite, greater in posterior part of each segment.
Specimen 4L: embryonic day 11.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS19: surface ectoderm Present Regionally restricted 4L Expression in superficial domain in dermis of the back that has a striped appearance but not sharp border.
TS19: limb Present Regionally restricted 4L Expression restricted to limb bud center.
Specimen 4M: embryonic day 11.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS19: inner ear Present 4M
Specimen 4N: embryonic day 11.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS19: floor plate Present Regionally restricted 4N Floor plate expression in a striped pattern.
Specimen 4O: embryonic day 12.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS20: back skin Present Regionally restricted 4O Expression in dermis of back loses its regular striped pattern and becomes more irregular and diffuse.
TS20: limb Present 4O
Specimen 4P: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: limb Present Regionally restricted 4P Expression extends into digits as they develop.
TS22: limb digit Present 4P Expression extends into digits as they develop.
Specimen 4Q: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: vibrissa follicle Present Regionally restricted 4Q Expression in outer cell sheath.
Specimen 4R: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: tooth epithelium Present 4R
Specimen 4S: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: limb mesenchyme Present Regionally restricted 4S Expression in subcutaneous connective tissue and tendon primordia.
TS22: limb cartilage condensation Absent 4S No expression in muscles or bones.
TS22: limb muscle Absent 4S No expression in muscles or bones.
Specimen 4T: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: blood vessel endothelium Present 4T
TS22: lung Present 4T
Specimen 4U: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: interventricular septum Present 4U
TS22: visceral pericardium Present 4U
Specimen 4V: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: pancreas epithelium Present Regionally restricted 4V Expression in epithelium of pancreas exocrine tissue.
Specimen 4W: embryonic day 14.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS22: liver vascular element Present Regionally restricted 4W Expression in surrounding large caliber vessels.
Specimen 4X: embryonic day 15.5; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS23: hair follicle Present Widespread 4X Expression in hair follicles throughout the body.
Specimen 5A: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present 5A
TS28: cerebral cortex Present 5A
TS28: hippocampus Present 5A
TS28: main olfactory bulb Present 5A
Specimen 5B: postnatal adult; DmdGt(ROSABetageo)1Mpd/Y (more )
Structure Level Pattern Image Note
TS28: bronchus epithelium Present 5B
Specimen not shown: postnatal adult; DmdGt(ROSABetageo)1Mpd/Y (more )
Structure Level Pattern Image Note
TS28: liver parenchyma Present Widespread Expression throughout hepatocytes.
Specimen 5C: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: liver parenchyma Present Spotted 5C Spotty expression in hepatocytes.
Specimen 5D: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: pancreas Present Non-Uniform 5D Expression in epithelium; authors report a mosaic pattern.
Specimen not shown: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: endocrine pancreas Present Expression in both exocrine and endocrine tissues.
TS28: exocrine pancreas Present Expression in both exocrine and endocrine tissues.
Specimen 5E: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 5E Expression in hippocampus, predominantly in the dentate gyrus.
Specimen 5F: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present 5F
Specimen 5G: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present 5G
Specimen 5H: postnatal adult; DmdGt(ROSABetageo)1Mpd/Dmd+ (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 5H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory