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Gene Expression Data
Assay Details
Assay
Reference: J:40904 Bouillet P, et al., Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein. Mech Dev. 1997 May;63(2):173-86
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5633927
Gene symbol: Stra6
Gene name: stimulated by retinoic acid gene 6
Antibody: Stra6 sntibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule epithelium Strong Regionally restricted 4A Expression is in the basal layer. The intensity varied between different tubules.
Specimen 4C: postnatal adult; Rarbtm1Ipc/Rarbtm1Ipc (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule epithelium Strong Regionally restricted 4C Expression in this mutant is the same as in wild-type.
Specimen 4E: postnatal adult; Raratm1Ipc/Raratm1Ipc (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule epithelium Strong Widespread 4E Expression is in almost all the tubules.
Specimen 5A: postnatal adult (more )
Note: Fixative was 4% paraformaldehyde, 0.2% picric acid and 0.1% glutaraldehyde. Stained sections were fixed with 5% glutaraldehyde in PBS, postfixed in 1% osmium tetroxide and infiltrated with Epon resin.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present Regionally restricted 5A Expression is in the plasma membrane of the basal pole of Sertoli cells.
TS28: spermatogonium Absent 5A
Specimen 5B: postnatal adult (more )
Note: Electron microscopy. Fixative was 4% paraformaldehyde, 0.2% picric acid and 0.1% glutaraldehyde. Stained sections were fixed with 5% glutaraldehyde in PBS, postfixed in 1% osmium tetroxide and infiltrated with Epon resin.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present Regionally restricted 5B Expression is in the plasma membrane of the basal pole of Sertoli cells.
TS28: spermatogonium Absent 5B
Specimen 6A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain meninges Present 6A
TS25: perioptic mesenchyme Present 6A
TS25: pigmented retinal epithelium Present 6A
TS25: retina inner nuclear layer Present 6A
TS25: optic nerve Present Regionally restricted 6A Expression is in the meninges of the optic nerve.
TS25: lens Present Regionally restricted 6A Expression is in the anteriormost part.
TS25: conjunctival sac Present Regionally restricted 6A Expression is in the epithelium lining the sac.
TS25: cornea Absent 6A
Specimen 6B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present 6B
Specimen not shown, A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: optic nerve Present Regionally restricted Expression is in the meninges surrounding the optic nerve.
TS28: meninges Present
TS28: brain blood vessel Present Regionally restricted Expression is in capillaries in the preoptic zone and in the medial cerebellar and ventral cochlear nuclei.
Specimen 7E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: choroid plexus Present 7E
Specimen 7F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain blood vessel Present 7F Expression is in microvessels.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory