Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Vav1tm1(EGFP/cre/ERT2)Wtsi
Name:	vav 1 oncogene; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID:	MGI:5633870
Synonyms:	Vav1tm1(EGFP/cre/ERT2)Hmgu
Gene:	Vav1  Location: Chr17:57586100-57635031 bp, + strand  Genetic Position: Chr17, 29.76 cM
Alliance:	Vav1tm1(EGFP/cre/ERT2)Wtsi page

Mutant Cell Line:	CEPD0077_3_B01
Germline Transmission:	Earliest citation of germline transmission: J:204812
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	EUCOMMTOOLS

Allele Type:    Targeted (Conditional ready, Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Vav1tm1(EGFP/cre/ERT2)Wtsi expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Vav1 (MGI:98923)   Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has loxP sites flanking exons 10 through 13, and inserted into the intron between exons 9 and 10 is one FRT site, an engrailed 2 splice acceptor sequence, an EGFP, and cre/ERT2 expression cassette, and a Rox flanked puromycin resistance cassette. (J:155845)

Activity:	Tissue activity of this recombinase allele
Driver:	Vav1 (mouse) Summary of all recombinase alleles driven by Vav1. Alliance mouse Vav1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vav1 Mutation:	58 strains or lines available

Original:	J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:	2 reference(s)