Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Mitftm2(EGFP/cre/ERT2)Wtsi
Name:	melanogenesis associated transcription factor; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID:	MGI:5633787
Synonyms:	Mitftm2(EGFP/cre/ERT2)Hmgu
Gene:	Mitf  Location: Chr6:97784013-97998310 bp, + strand  Genetic Position: Chr6, 45.05 cM
Alliance:	Mitftm2(EGFP/cre/ERT2)Wtsi page

Mutant Cell Line:	CEPD0085_4_C09
Germline Transmission:	Earliest citation of germline transmission: J:204812
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	EUCOMMTOOLS

Allele Type:    Targeted (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Mitftm2(EGFP/cre/ERT2)Wtsi expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Mitf (MGI:104554)   Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted in the intron between exons 5 and 6. A single loxP site is inserted in intron 6. (J:155845)

Activity:	Tissue activity of this recombinase allele
Driver:	Mitf (mouse) Summary of all recombinase alleles driven by Mitf. Alliance mouse Mitf gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mitf Mutation:	72 strains or lines available

Original:	J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:	2 reference(s)