About   Help   FAQ
Cdh2tm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Cdh2tm2(EGFP/cre/ERT2)Wtsi
Name: cadherin 2; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:5632395
Synonyms: Cdh2tm2(EGFP/cre/ERT2)Hmgu
Gene: Cdh2  Location: Chr18:16721934-16942303 bp, - strand  Genetic Position: Chr18, 10.1 cM
Alliance: Cdh2tm2(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0081_3_C04
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase, Reporter)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Cdh2tm2(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation detailsAccording to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette that replaces exon 1. A single loxP site is inserted in intron 2. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdh2 (mouse)
Summary of all recombinase alleles driven by Cdh2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdh2 Mutation:  50 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory