Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mir34atm2.1Hher
Name:	microRNA 34a; targeted mutation 2.1, Heiko Hermeking
MGI ID:	MGI:5629848
Synonyms:	mir-34aloxP
Gene:	Mir34a  Location: Chr4:150152911-150153012 bp, + strand  Genetic Position: Chr4, 80.85 cM
Alliance:	Mir34atm2.1Hher page

Germline Transmission:	Earliest citation of germline transmission: J:175978
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of the microRNA. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the microRNA. Flp-mediated recombination remoced the selection cassette and left the microRNA floxed. This allele was used to generate Mir34atm1Hher. (J:175978)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir34a Mutation:	9 strains or lines available

Original:	J:175978 Hwang CI, et al., Wild-type p53 controls cell motility and invasion by dual regulation of MET expression. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14240-5
All:	5 reference(s)