Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ggcxtm1Sinos
Name:	gamma-glutamyl carboxylase; targeted mutation 1, Satoshi Inoue
MGI ID:	MGI:5621178
Synonyms:	Ggcxflox
Gene:	Ggcx  Location: Chr6:72391291-72407695 bp, + strand  Genetic Position: Chr6, 32.27 cM, cytoband C3
Alliance:	Ggcxtm1Sinos page

Germline Transmission:	Earliest citation of germline transmission: J:212951
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 6. A neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 6. (J:212951)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ggcx Mutation:	36 strains or lines available

Original:	J:212951 Azuma K, et al., Liver-specific gamma-glutamyl carboxylase-deficient mice display bleeding diathesis and short life span. PLoS One. 2014;9(2):e88643
All:	4 reference(s)