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Gene Expression Data
Assay Details
Assay
Reference: J:199420 Mujahid S, et al., MiR-221 and miR-130a regulate lung airway and vascular development. PLoS One. 2013;8(2):e55911
Assay type: RNA in situ
MGI Accession ID: MGI:5620756
Gene symbol: Mir221
Gene name: microRNA 221
Probe: miR-221 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1B E16/16': embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: bronchiole epithelium Strong 1B E16' , 1B E16
TS24: bronchiole Strong 1B E16 , 1B E16' Expressed in bronchiolar epithelium and mesenchyme.
TS24: lung mesenchyme Strong Regionally restricted 1B E16' , 1B E16 Expressed in bronchiolar mesenchyme.

Specimen 1B E17/17': embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: bronchiole epithelium Present 1B E17' , 1B E17 Decreased expression.
TS25: lung mesenchyme Strong Regionally restricted 1B E17 , 1B E17' Expressed in bronchiolar mesenchyme.
TS25: bronchiole Strong Regionally restricted 1B E17' , 1B E17 Mesenchymal expression remained strong and epithelial expression decreased.

Specimen 1B E18/18': embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: bronchiole epithelium Trace 1B E18' , 1B E18 Expression was only minimally present.
TS26: lung mesenchyme Present Regionally restricted 1B E18' , 1B E18 Expression in the bronchiolar mesenchyme was more diffuse.
TS26: bronchiole Present Regionally restricted 1B E18 , 1B E18' Expression in the bronchiolar mesenchyme was more diffuse, and expression in bronchiolar epithelium was only minimally present.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory