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Gene Expression Data
Assay Details
Assay
Reference: J:30430 Schonemann MD, et al., Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes Dev. 1995 Dec 15;9(24):3122-35
Assay type: RNA in situ
MGI Accession ID: MGI:5620381
Gene symbol: Crh
Gene name: corticotropin releasing hormone
Probe: CRH probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4a left: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus Strong 4a left Expressed in neurosecretory neurons.
TS28: lateral hypothalamic area Present Scattered 4a left
TS28: diencephalon Present Regionally restricted 4a left Expressed in scattered cells in the substantia innominata.

Specimen 4a right: postnatal day 6; Pou3f2tm1Rsd/Pou3f2tm1Rsd (more )
Structure Level Pattern Image Note
TS28: paraventricular hypothalamic nucleus Absent 4a right
TS28: lateral hypothalamic area Present Scattered 4a right
TS28: diencephalon Present Regionally restricted 4a right Expressed in scattered cells in the substantia innominata.

Specimen 6A e13 upper right: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: hypothalamus Absent 6A e13 upper right

Specimen 6A e13 lower right: embryonic day 13.0; Pou3f2tm1Rsd/Pou3f2tm1Rsd (more )
Structure Level Pattern Image Note
TS21: hypothalamus Absent 6A e13 lower right

Specimen 6A e16 upper right: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: hypothalamus Present 6A e16 upper right Relatively abundant.

Specimen 6A e16 lower right: embryonic day 16.0; Pou3f2tm1Rsd/Pou3f2tm1Rsd (more )
Structure Level Pattern Image Note
TS24: hypothalamus Absent 6A e16 lower right

Specimen 6A e19 upper right: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: hypothalamus Present 6A e19 upper right

Specimen 6A e19 lower right: embryonic day 19.0; Pou3f2tm1Rsd/Pou3f2tm1Rsd (more )
Structure Level Pattern Image Note
TS26: hypothalamus Present Single cells 6A e19 lower right Occasional expressing neurons was seen.

Specimen not shown: postnatal day 6; Pou3f2tm1Rsd/Pou3f2tm1Rsd (more )
Structure Level Pattern Image Note
TS28: amygdala Present Same as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory