About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:213957 Howard JM, et al., Tcf3 expression marks both stem and progenitor cells in multiple epithelia. Development. 2014 Aug;141(16):3143-52
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5620303
Gene symbol: Tcf7l1
Gene name: transcription factor 7 like 1 (T cell specific, HMG box)
Reporter: GFP
Antibody: anti-GFP (ab13970)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The authors described two anti-GFP antibodies; it is possible that MGI:3763264 was used to obtain some or all of these data.
Results
Specimen 1M: postnatal day 21; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1+ (more )
Note: Back skin. Telogen hair cycle phase.
Structure Level Pattern Image Note
TS28: coat hair follicle Present 1M Expression is detected in the hair follicle bulge.
TS28: dermis papillary layer Present 1M
TS28: sebaceous gland Absent 1M Non-specific staining.

Specimen 1N: postnatal day 30; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1+ (more )
Note: Back skin. Anagen hair cycle phase.
Structure Level Pattern Image Note
TS28: coat hair follicle Present 1N Expression is detected in the hair follicle bulge.
TS28: hair outer root sheath Present 1N
TS28: sebaceous gland Absent 1N Non-specific staining.

Specimen 1O: postnatal day 30; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1+ (more )
Note: Back skin. Anagen hair cycle phase
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 1O

Specimen 1P: postnatal day 21; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1tm1.1(cre/ERT2)Hng (more )
Note: Back skin. Telogen hair cycle phase.
Structure Level Pattern Image Note
TS28: coat hair follicle Present 1P Expression is detected in the hair follicle bulge.
TS28: dermis papillary layer Present 1P
TS28: sebaceous gland Absent 1P

Specimen 1Q: postnatal day 30; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1tm1.1(cre/ERT2)Hng (more )
Note: Back skin. Anagen hair cycle phase.
Structure Level Pattern Image Note
TS28: coat hair follicle Present 1Q Expression is detected in the hair follicle bulge.
TS28: hair outer root sheath Present 1Q
TS28: sebaceous gland Absent 1Q Non-specific staining.

Specimen 1R: postnatal day 30; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1tm1.1(cre/ERT2)Hng (more )
Note: Back skin. Anagen hair cycle phase.
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 1R

Specimen S1I: postnatal adult; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1+ (more )
Structure Level Pattern Image Note
TS28: esophagus basal epithelium Present S1I

Specimen S1J: postnatal adult; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1+ (more )
Structure Level Pattern Image Note
TS28: tongue epithelium Present S1J Expression is detected in the epithelial basal layer.

Specimen S1K: postnatal adult; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1+ (more )
Structure Level Pattern Image Note
TS28: foot skin Present S1K Expression is detected in the epithelial basal layer.

Specimen S1L: postnatal adult; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1tm1.1(cre/ERT2)Hng (more )
Structure Level Pattern Image Note
TS28: esophagus basal epithelium Present S1L

Specimen S1M: postnatal adult; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1tm1.1(cre/ERT2)Hng (more )
Structure Level Pattern Image Note
TS28: tongue epithelium Present S1M Expression is detected in the epithelial basal layer.

Specimen S1N: postnatal adult; Tcf7l1tm1.1(cre/ERT2)Hng/Tcf7l1tm1.1(cre/ERT2)Hng (more )
Structure Level Pattern Image Note
TS28: foot skin Present S1N Expression is detected in the epithelial basal layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory