Pax3tm1.1(cre/ERT2)Lepr
Targeted Allele Detail
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Symbol: |
Pax3tm1.1(cre/ERT2)Lepr |
Name: |
paired box 3; targeted mutation 1.1, Christoph Lepper |
MGI ID: |
MGI:5620010 |
Synonyms: |
Pax3CE |
Gene: |
Pax3 Location: Chr1:78077904-78173771 bp, - strand Genetic Position: Chr1, 39.79 cM
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Alliance: |
Pax3tm1.1(cre/ERT2)Lepr page
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Germline Transmission: |
Earliest citation of germline transmission:
J:210509
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6 x 129
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intragenic deletion
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Pax3tm1.1(cre/ERT2)Lepr expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pax3 (MGI:97487) |
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Mutation details: A rabbit beta-globin intron, cre/ERT2 fusion gene, SV40 late polyadenylation signal and FRT-flanked neomycin cassette replaced the coding sequence in exon 1. Flp-mediated recombination removed the selection cassette.
(J:210509)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pax3
(mouse)
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Original: |
J:210509 Southard S, et al., A series of Cre-ER(T2) drivers for manipulation of the skeletal muscle lineage. Genesis. 2014 Aug;52(8):759-70 |
All: |
2 reference(s) |
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