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Gene Expression Data
Assay Details
Assay
Reference: J:141806 Barle EL, et al., Expression of oestrogen receptor alpha during development of the skeleton in mice fetuses: immunohistochemical study. Anat Histol Embryol. 2008 Dec;37(6):408-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5619866
Gene symbol: Esr1
Gene name: estrogen receptor 1 (alpha)
Antibody: anti-ERalpha
Detection system: Secondary antibody
Results
Specimen 1a: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: sphenoid bone Present Regionally restricted 1a Expression is in chondrocytes in the resting and proliferating zone at the basilar part of the spenoid bone precursor.

Specimen 1b: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basioccipital cartilage condensation Present Regionally restricted 1b Expression is in hypertrophic chondrocytes and osteocytes.

Specimen 1c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible Absent 1c

Specimen 1d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible Present Single cells 1d Expression is in osteoblasts.

Specimen 1e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metatarsus cartilage condensation Absent 1e

Specimen 1f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metatarsus cartilage condensation Present Regionally restricted 1f Expression is in chondrocytes.

Specimen 1g: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mandible Present Regionally restricted 1g Expression is in osteoblasts.

Specimen 1h: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: clavicle Present Regionally restricted 1h Expression is in the osteoblasts.

Specimen 2a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: C2 vertebra Present Regionally restricted 2a Expression is in osteoblasts.

Specimen 2b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: sacral vertebra Present Regionally restricted 2b Expression is in hypertrophic chondrocytes.

Specimen 2c: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forelimb phalanx Absent 2c

Specimen 2d: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forelimb phalanx Present Regionally restricted 2d Expression is in chondrocytes.

Specimen 2e: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: maxilla Present Regionally restricted 2e Expression is in osteoblasts.

Specimen 2f: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: vertebra Present Regionally restricted 2f Expression is in osteoblasts and osteocytes.

Specimen 2g: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cranium Present Regionally restricted 2g Expression is in osteoblasts.

Specimen Table 2 E 14.5 male: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cranium Present Regionally restricted Expression is in chondrocytes and osteocytes at the base of the skull.
TS22: humerus cartilage condensation Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: radius cartilage condensation Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: rib cartilage condensation Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: scapula cartilage condensation Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: ulna cartilage condensation Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: vertebral cartilage condensation Present Regionally restricted Expression is in chondrocytes and is absent in osteocytes.
TS22: femur cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.
TS22: fibula cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.
TS22: mandible Absent Expression is absent in chondrocytes and osteocytes.
TS22: metacarpus cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.
TS22: metatarsus cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.
TS22: sternum Absent Expression is absent in chondrocytes and osteocytes.
TS22: tibia cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.

Specimen Table 2 E 14.5 female: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cranium Present Regionally restricted Expression is in chondrocytes and osteocytes at the base of the skull.
TS22: humerus cartilage condensation Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: rib cartilage condensation Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS22: hyoid cartilage condensation Present Regionally restricted Expression is in osteocytes.
TS22: metatarsus cartilage condensation Present Regionally restricted Expression is in chondrocytes and is absent in osteocytes.
TS22: pelvic girdle skeleton Present Regionally restricted Expression is in chondrocytes and is absent in osteocytes.
TS22: vertebral cartilage condensation Present Regionally restricted Expression is in chondrocytes and is absent in osteocytes.
TS22: femur cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.
TS22: fibula cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.
TS22: sternum Absent Expression is absent in chondrocytes and osteocytes.
TS22: tibia cartilage condensation Absent Expression is absent in chondrocytes and osteocytes.

Specimen Table 2 E 15.5 male: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cranium Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes at the base of the skull.
TS23: clavicle Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: femur Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: hyoid Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: scapula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: vertebra Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: ethmoid bone primordium Absent Expression is absent in chondrocytes and osteocytes.
TS23: pelvic girdle skeleton Absent Expression is absent in chondrocytes and osteocytes.
TS23: sternum Absent Expression is absent in chondrocytes and osteocytes.
TS23: forelimb phalanx Absent Expression is in osteocytes.
TS23: hindlimb phalanx Absent Expression is in osteocytes.
TS23: metacarpus Absent Expression is in osteocytes.
TS23: metatarsus mesenchyme Absent Expression is in osteocytes.

Specimen Table 2 E 15.5 female: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cranium Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes at the base of the skull.
TS23: clavicle Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: femur Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: fibula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: humerus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: hyoid Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: radius Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: scapula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: tibia Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: ulna Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: vertebra Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS23: metacarpus Present Regionally restricted Expression is in chondrocytes and is absent in osteocytes.
TS23: ethmoid bone primordium Absent Absent in osteocytes.
TS23: forelimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS23: hindlimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS23: metatarsus mesenchyme Absent Expression is absent in chondrocytes and osteocytes.
TS23: sternum Absent Expression is absent in chondrocytes and osteocytes.

Specimen Table 2 E 16.5 male: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vertebra Present Expression is in chondrocytes and osteocytes.
TS24: cranium Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes at the base of the skull.
TS24: femur Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: fibula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: pelvic girdle skeleton Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: scapula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: tibia Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: ethmoid bone Absent Expression is absent in chondrocytes and osteocytes.
TS24: forelimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS24: hindlimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS24: metacarpus Absent Expression is absent in chondrocytes and osteocytes.
TS24: sternum Absent Expression is absent in chondrocytes and osteocytes.
TS24: hyoid Absent Expression is absent in chondrocytes.

Specimen Table 2 E 16.5 female: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cranium Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes at the base of the skull.
TS24: femur Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: fibula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: humerus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: pelvic girdle skeleton Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: tibia Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: vertebra Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS24: ethmoid bone Absent Expression is absent in chondrocytes and osteocytes.
TS24: forelimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS24: hindlimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS24: metatarsus Absent Expression is absent in chondrocytes and osteocytes.
TS24: sternum Absent Expression is absent in chondrocytes and osteocytes.

Specimen Table 2 E 17.5 male: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: humerus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: radius Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: ulna Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: vertebra Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: forelimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS25: hindlimb phalanx Absent Expression is absent in chondrocytes and osteocytes.
TS25: sternum Absent Expression is absent in chondrocytes and osteocytes.

Specimen Table 2 E 17.5 female: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cranium Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes at the base of the skull.
TS25: femur Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: humerus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: hyoid Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: metacarpus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: pelvic girdle skeleton Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: radius Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: scapula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: tibia Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: ulna Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: vertebra Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS25: forelimb phalanx Present Regionally restricted Expression is in chondrocytes and absent in osteocytes.
TS25: hindlimb phalanx Present Regionally restricted Expression is in chondrocytes and absent in osteocytes.
TS25: metatarsus Present Regionally restricted Expression is in chondrocytes and absent in osteocytes.
TS25: ethmoid bone Absent Expression is absent in chondrocytes and osteocytes.
TS25: sternum Absent Expression is absent in chondrocytes and osteocytes.

Specimen Table 2 E 18.5 male: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cranium Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes at the base of the skull.
TS26: ethmoid bone Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: femur Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: fibula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: forelimb phalanx Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: hindlimb phalanx Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: humerus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: hyoid Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: metatarsus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: pelvic girdle skeleton Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: radius Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: scapula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: sternum Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: tibia Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: ulna Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: vertebra Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.

Specimen Table 2 E 18.5 female: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cranium Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes at the base of the skull.
TS26: femur Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: humerus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: mandible Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: maxilla Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: metatarsus Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: pelvic girdle skeleton Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: radius Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: rib Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: scapula Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: ulna Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: vertebra Present Regionally restricted Expression is in osteocytes and is absent in chondrocytes.
TS26: forelimb phalanx Present Regionally restricted Expression is in chondrocytes and absent in osteocytes.
TS26: hindlimb phalanx Present Regionally restricted Expression is in chondrocytes and absent in osteocytes.

Specimen not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: skeleton Absent


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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory