Gene Expression Data
Assay Details
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Assay
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Reference:
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J:109334
Schafer K, et al., The homeobox gene Lbx1 specifies a subpopulation of cardiac neural crest necessary for normal heart development. Circ Res. 2003 Jan 10;92(1):73-80
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5619121
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Gene symbol:
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Lbx1
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Gene name:
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ladybird homeobox 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1A:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1B:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1B:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1C:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1C:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1F:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1F:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1G:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1G:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1H/M:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more )
Note: Double labeled: blue - Lbx1 reporter; brown - Gja5 (assay MGI:5619419).
Specimen
1H/M:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: blue - Lbx1 reporter; brown - Gja5 (assay MGI:5619419).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: migrating neural crest |
Present |
Single cells |
1H
,
1M
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Expressed in small clusters of cells leaving the neural tube to the caudal branchial arch and the truncus arteriosus. Positive cells were still relatively rare.
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Specimen
1I:
embryonic day 10.5; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1I:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1J:
embryonic day 11.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1J:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1K:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1K:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1L:
embryonic day 9.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1L:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1N:
(close )
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Genetic Background:
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involves: 101/H * 129S4/SvJae * C3H/HeH * C57BL/6
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
Pax3Sp-1H/Pax3Sp-1H
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Present |
Regionally restricted |
1N
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Expressed in the dorsal region. The myogenic precursor cells migrating toward the branchial arch is absent, compared with the Lbx1 heterozygous embryo.
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Specimen
1O:
embryonic day 11.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
1O:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
3A:
embryonic day 11.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
3A:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
3B:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1tm1Thbr
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7A:
embryonic day 13.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
7A:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: heart |
Absent |
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7A
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Specimen
7B:
(close )
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Genetic Background:
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involves: 101/H * 129S4/SvJae * C3H/HeH * C57BL/6
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
Pax3Sp-1H/Pax3Sp-1H
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: heart |
Present |
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7B
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A significant upregulation compared with the Lbx1 heterozygous embryo.
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Specimen
7C:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1tm1Thbr
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: heart |
Present |
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7C
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A significant upregulation compared with the Lbx1 heterozygous embryo.
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Specimen
7D:
embryonic day 12.5; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
7D:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: heart |
Absent |
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7D
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Specimen
7E:
(close )
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Genetic Background:
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involves: 101/H * 129S4/SvJae * C3H/HeH * C57BL/6
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
Pax3Sp-1H/Pax3Sp-1H
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: heart |
Absent |
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7E
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Specimen
7F:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1tm1Thbr
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7G:
embryonic day 13.0; Lbx1tm1Thbr/Lbx1 +
(more )
Specimen
7G:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: heart |
Absent |
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7G
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Specimen
7H:
(close )
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Genetic Background:
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involves: 101/H * 129S4/SvJae * C3H/HeH * C57BL/6
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1+
Pax3Sp-1H/Pax3Sp-1H
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: heart |
Present |
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7H
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A significant upregulation compared with the Lbx1 heterozygous embryo.
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Specimen
7I:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Lbx1tm1Thbr/Lbx1tm1Thbr
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: heart |
Present |
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7I
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A significant upregulation compared with the Lbx1 heterozygous embryo.
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Analysis Tools