Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rflnatm1Tfur
Name:	refilin A; targeted mutation 1, Takahisa Furukawa
MGI ID:	MGI:5618543
Synonyms:	Cfm2-
Gene:	Rflna  Location: Chr5:125080512-125089611 bp, + strand  Genetic Position: Chr5, 63.95 cM, cytoband F
Alliance:	Rflnatm1Tfur page

Germline Transmission:	Earliest citation of germline transmission: J:210363
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A genomic region including all of exon 1 was replaced with a pgk-neo cassette via homologous recombination. Western blot analysis confirmed the absence of protein expression in femurs from homozygous mice. (J:210363)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rflna Mutation:	7 strains or lines available

Original:	J:210363 Mizuhashi K, et al., Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements. Hum Mol Genet. 2014 Jun 1;23(11):2953-67
All:	1 reference(s)