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Tg(ACTA1-Dmd)2197Chmb
Transgene Detail
Summary
Symbol: Tg(ACTA1-Dmd)2197Chmb
Name: transgene insertion 2197, Jeffrey S Chamberlain
MGI ID: MGI:5618459
Synonyms: Dp116
Transgene: Tg(ACTA1-Dmd)2197Chmb  Location: unknown  
Alliance: Tg(ACTA1-Dmd)2197Chmb page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic
Mutation:    Insertion
 
Mutation detailsA cDNA construct that expresses the full-length Dp116 isoform and an N-terminal Flag tag was generated by PCR and cloned downstream of the human skeletal alpha-actin promoter. The Dp116 isoform is a non-muscle form of dystrophin and includes the entire WW domain but only two complete repeats from the rod domain. (J:107808)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:107808 Judge LM, et al., Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex. J Cell Sci. 2006 Apr 15;119(Pt 8):1537-46
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory