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Gene Expression Data
Assay Details
Assay
Reference: J:135988 Yamanaka Y, et al., Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality. Mech Dev. 2008 May-Jun;125(5-6):441-50
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5617034
Gene symbol: Aurkb
Gene name: aurora kinase B
Antibody: anti-AIM-1 (Clone 6)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 6A Normal: embryonic day 3.5 (more )
Note: Double labeled: green - Aurkb; red - a/b-Tubulin.
Structure Level Pattern Image Note
TS5: blastocyst Present 6A Merge top , 6A AuroraB Normal
Specimen 6A Abnormal: embryonic day 3.5; Cdca8tm1Tatn/Cdca8tm1Tatn (more )
Note: Double labeled: green - Aurkb; red - a/b-Tubulin.
Structure Level Pattern Image Note
TS5: blastocyst Present Diffuse 6A AuroraB Abnormal , 6A Merge bottom
Specimen 6B Normal: embryonic day 3.5 (more )
Note: Double labeled: green - Aurkb; red - Birc5 (assay MGI:5617035).
Structure Level Pattern Image Note
TS5: blastocyst Present 6B AuroraB top , 6B Merge top
Specimen 6B Abnormal middle: embryonic day 3.5; Cdca8tm1Tatn/Cdca8tm1Tatn (more )
Note: Double labeled: green - Aurkb; red - Birc5 (assay MGI:5617035).
Structure Level Pattern Image Note
TS5: blastocyst Present Diffuse 6B AuroraB middle , 6B Merge middle
Specimen 6B Abnormal bottom: embryonic day 3.5; Cdca8tm1Tatn/Cdca8tm1Tatn (more )
Note: Double labeled: green - Aurkb; red - Birc5 (assay MGI:5617035).
Structure Level Pattern Image Note
TS5: blastocyst Present Diffuse 6B Merge bottom , 6B AuroraB bottom
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory