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Gene Expression Data
Assay Details
Assay
Reference: J:79191 Denier C, et al., Krit1/cerebral cavernous malformation 1 mRNA is preferentially expressed in neurons and epithelial cells in embryo and adult. Mech Dev. 2002 Sep;117(1-2):363
Assay type: RNA in situ
MGI Accession ID: MGI:5616088
Gene symbol: Krit1
Gene name: KRIT1, ankyrin repeat containing
Probe: Krit1 cDNA
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1A/B: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present Ubiquitous 1A/B

Specimen 1A/B mother: postnatal adult (more )
Note: Pregnant dpc 7.5.
Structure Level Pattern Image Note
TS28: uterus Weak 1A/B

Specimen 1D/E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Ubiquitous 1D/E
TS13: embryo Present Ubiquitous 1D/E

Specimen 1D/E mother: postnatal adult (more )
Note: Pregnant dpc 8.5.
Structure Level Pattern Image Note
TS28: uterus Weak 1D/E

Specimen 1G/H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Ubiquitous 1G/H
TS15: embryo Present Ubiquitous 1G/H
TS15: dorsal aorta Weak 1G/H
TS15: blood vessel Weak Regionally restricted 1G/H Expression is in the intersomitic, head, and neck vesels.

Specimen 1G/H mother: postnatal adult (more )
Note: Pregnant dpc 9.5.
Structure Level Pattern Image Note
TS28: uterus Weak 1G/H

Specimen 2A/B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Uniform 2A/B
TS17: dorsal aorta Weak 2A/B
TS17: blood vessel Weak Regionally restricted 2A/B Expression is in large vessels, absent in small blood vessels and capillaries.

Specimen not shown E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: intraembryonic coelom Present Regionally restricted Expression is in coelomic epithelium.
TS17: gut epithelium Present Regionally restricted Expression is in intestinal epithelium.
TS17: cardiac muscle tissue Present
TS17: esophagus Present
TS17: optic cup Present
TS17: stomach Present
TS17: embryo mesenchyme Moderate Regionally restricted Expression is in mesenchyme adjacent to expressing neural tube and coelomic and intestinal epithelia.
TS17: dermomyotome Moderate
TS17: limb Moderate
TS17: sclerotome Moderate
TS17: blood vessel Weak Regionally restricted Expression is in large vessels.
TS17: dorsal aorta Weak
TS17: heart Weak

Specimen not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Strong
TS19: neural tube Present Widespread
TS19: cardiac muscle tissue Present
TS19: esophagus Present
TS19: intestine Present
TS19: retina Present
TS19: stomach Present
TS19: intraembryonic coelom Present Regionally restricted Expression is in coelomic epithelium.
TS19: embryo mesenchyme Moderate Regionally restricted Expression is in mesenchyme adjacent to expressing neural tube and coelomic and intestinal epithelia.
TS19: dermomyotome Moderate
TS19: limb Moderate
TS19: sclerotome Moderate
TS19: blood vessel Weak Regionally restricted Expression is in large vessels.
TS19: dorsal aorta Weak
TS19: heart Weak

Specimen not shown E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Strong
TS20: spinal cord Present Widespread
TS20: cardiac muscle tissue Present
TS20: esophagus Present
TS20: intestine Present
TS20: intestine epithelium Present
TS20: retina Present
TS20: skeletal muscle Present
TS20: skin Present
TS20: stomach Present
TS20: trachea epithelium Present
TS20: intraembryonic coelom Present Regionally restricted Expression is in coelomic epithelium.
TS20: lung epithelium Present Regionally restricted Expression is in bronchial epithelium.
TS20: embryo mesenchyme Moderate Regionally restricted Expression is in mesenchyme adjacent to expressing neural tube and coelomic and intestinal epithelia.
TS20: dermomyotome Moderate
TS20: limb Moderate
TS20: pre-cartilage condensation Moderate
TS20: sclerotome Moderate
TS20: blood vessel Weak Regionally restricted Expression is in large vessels.
TS20: dorsal aorta Weak
TS20: heart Weak

Specimen 2D/E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: central nervous system Present Regionally restricted 2D/E Expression is in subventricular layers.
TS22: ganglionic eminence Present Regionally restricted 2D/E Expression is in the ganglionic eminence projecting into the third ventricle.
TS22: brainstem Present 2D/E
TS22: thalamus Present 2D/E
TS22: trigeminal ganglion Present 2D/E
TS22: blood vessel Weak 2D/E

Specimen 2G/H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Strong 2G/H
TS22: cardiac muscle tissue Present 2G/H
TS22: dorsal aorta Present 2G/H

Specimen not shown E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: epidermis Present
TS22: esophagus epithelium Present
TS22: hair follicle Present
TS22: incisor Present
TS22: intestine epithelium Present
TS22: lobar bronchus epithelium Present
TS22: seminiferous cord Present
TS22: skeletal muscle Present
TS22: stomach epithelium Present
TS22: trachea epithelium Present
TS22: vibrissa Present
TS22: cartilage Weak
TS22: esophagus mesenchyme Weak
TS22: intestine mesenchyme Weak
TS22: lung parenchyma Weak
TS22: stomach mesenchyme Weak

Specimen not shown E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dorsal root ganglion Strong
TS24: bone Strong Regionally restricted Expression is in ossification centers.
TS24: brain Present Regionally restricted Expression is mostly detected within layers containing neuronal cells as compared to layers enriched in glial cells.
TS24: cardiac muscle tissue Present
TS24: epidermis Present
TS24: esophagus epithelium Present
TS24: hair follicle Present
TS24: intestine epithelium Present
TS24: liver Present
TS24: pancreas Present
TS24: retina Present
TS24: seminiferous cord Present
TS24: skeletal muscle Present
TS24: spleen Present
TS24: stomach epithelium Present
TS24: tooth Present
TS24: trachea epithelium Present
TS24: vibrissa Present
TS24: bronchiole epithelium Present Regionally restricted Expression is in bronchial epithelium.
TS24: aorta Weak
TS24: esophagus mesenchyme Weak
TS24: intestine mesenchyme Weak
TS24: lung parenchyma Weak
TS24: stomach mesenchyme Weak
TS24: blood vessel Weak Regionally restricted Expression is in the intersomitic, head, and neck vesels.

Specimen not shown E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Strong
TS26: brain Present Regionally restricted Expression is mostly detected within layers containing neuronal cells as compared to layers enriched in glial cells.
TS26: cranium Present Regionally restricted Expression is in peri-osteal ossification regions.
TS26: vertebra Present Regionally restricted Expression is in peri-osteal ossification regions.
TS26: bronchiole epithelium Present
TS26: cardiac muscle tissue Present
TS26: epidermis Present
TS26: esophagus epithelium Present
TS26: hair follicle Present
TS26: intestine epithelium Present
TS26: liver Present
TS26: pancreas Present
TS26: retina Present
TS26: seminiferous cord Present
TS26: skeletal muscle Present
TS26: spleen Present
TS26: stomach epithelium Present
TS26: tooth Present
TS26: trachea epithelium Present
TS26: vibrissa Present
TS26: esophagus mesenchyme Weak
TS26: intestine mesenchyme Weak
TS26: lung parenchyma Weak
TS26: stomach mesenchyme Weak
TS26: blood vessel Trace Regionally restricted Expression is in the intersomitic, head, and neck vesels.
TS26: aorta Trace

Specimen 2J/K: embryonic day 20.5 (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Strong 2J/K
TS26: spinal cord Present Regionally restricted 2J/K Expression is in the grey matter.
TS26: spinal cord meninges Weak 2J/K
TS26: sympathetic ganglion Weak 2J/K

Specimen 2M/N: embryonic day 20.5 (more )
Structure Level Pattern Image Note
TS26: brain Present Regionally restricted 2M/N Expression is mostly detected within layers containing neuronal cells as compared to layers enriched in glial cells.
TS26: choroid plexus Weak Regionally restricted 2M/N

Specimen not shown E20.5: embryonic day 20.5 (more )
Structure Level Pattern Image Note
TS26: epidermis Present
TS26: hair follicle Present
TS26: skeletal muscle Present
TS26: tooth Present
TS26: vibrissa Present
TS26: cranium Present Regionally restricted Expression is in peri-osteal ossification regions.
TS26: vertebra Present Regionally restricted Expression is in peri-osteal ossification regions.
TS26: blood vessel Trace Regionally restricted Expression is in the intersomitic, head, and neck vesels.
TS26: aorta Trace

Specimen 2P/Q: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong 2P/Q
TS28: brain white matter Absent 2P/Q
TS28: capillary Absent 2P/Q

Specimen 2S/T: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 2S/T
TS28: brain white matter Absent 2S/T
TS28: capillary Absent 2S/T

Specimen 2V/W: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 2V/W
TS28: cerebellum granule cell layer Present 2V/W
TS28: habenula Present 2V/W
TS28: main olfactory bulb Present 2V/W
TS28: brain white matter Absent 2V/W
TS28: capillary Absent 2V/W

Specimen 2Y/Z: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: retina Strong 2Y/Z

Specimen not shown Adult: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Strong
TS28: bronchiole epithelium Present
TS28: epidermis Present
TS28: hair follicle Present
TS28: liver Present
TS28: pancreas Present
TS28: spleen Present
TS28: stomach epithelium Present
TS28: trachea epithelium Present
TS28: vibrissa Present
TS28: cardiac muscle tissue Weak
TS28: choroid plexus Weak
TS28: lung parenchyma Weak
TS28: meninges Weak
TS28: stomach wall Weak
TS28: blood vessel Absent Absent in large blood vessels.
TS28: aorta Absent

Specimen 3A/B: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: intestine epithelium Present 3A/B
TS28: intestine wall Weak 3A/B

Specimen 3D/E: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: esophagus epithelium Present 3D/E
TS28: esophagus wall Weak 3D/E

Specimen 3G/H: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: spermatocyte Strong 3G/H

Specimen 3J/K: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: ovary follicle Strong 3J/K


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory