About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:213596 Lietman CD, et al., Connective tissue alterations in Fkbp10-/- mice. Hum Mol Genet. 2014 Sep 15;23(18):4822-31
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5615612
Gene symbol: Fkbp10
Gene name: FK506 binding protein 10
Reporter: lacZ
Direct Detection
Results
Specimen 1B upper left: embryonic day 13.5; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS21: skeleton Weak 1B upper left
Specimen 1B upper right: embryonic day 15.5; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS23: skeleton Present 1B upper right
Specimen 1C upper: embryonic day 17.5; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS25: long bone Strong Regionally restricted 1C upper , 1C Growth Plate , 1C Long bone Intense expression in the developing cortical bone. Strong staining of the resting zone. Expressed in the condensing mesenchyme with low levels in the proliferative zone and no expression in the hypertrophic region.
TS25: vertebra Present 1C upper , 1C Spine
TS25: rib Present 1C upper , 1C Ribs
TS25: heart Present Regionally restricted 1C Heart , 1C upper Expressed in the large vessels of the heart.
TS25: lung Present Regionally restricted 1C Lung , 1C upper Expressed in the large vessels of the lung.
TS25: collecting duct Present 1C upper , 1C Kidney
TS25: glomerular capillary system of maturing glomerular tuft Present 1C upper , 1C Kidney
TS25: renal distal tubule Present 1C upper , 1C Kidney
TS25: intestine epithelium Present Regionally restricted 1C Intestine , 1C upper Expressed in the tips of the villi.
TS25: skeletal muscle Present Regionally restricted 1C Long bone , 1C upper Expressed in the developing ligaments.
Specimen 1D upper: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: ligament Present 1D upper left , 1D upper right
TS28: tendon Present 1D upper left , 1D upper right
TS28: periosteum Present 1D upper middle , 1D upper left , 1D upper right
TS28: bone Present Regionally restricted 1D upper middle , 1D upper right , 1D upper left No staining is evident in the growth plate.
Specimen S1 right: embryonic day 15.5; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS23: skeleton Present S1_right
Specimen S2B: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: intervertebral disc Present S2_B
Specimen S2C: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: aorta Absent S2_C
Specimen S2D: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: skin Absent S2_D
Specimen S2E: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: skeletal muscle Absent S2_E
Specimen S2F: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: lung Absent S2_F
Specimen S2G: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: liver Absent S2_G
Specimen S2H: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: metanephros Absent S2_H
Specimen S2I: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: intestine Absent S2_I
Specimen S2J: postnatal month 2; Fkbp10tm2a(EUCOMM)Wtsi/Fkbp10+ (more )
Note: Fixed in 0.5% glutaraldehyde, 2.0% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Absent S2_J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory