Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(ZP2*)4Dean
Name:	transgene insertion 4, Jurrien Dean
MGI ID:	MGI:5613982
Synonyms:	mo/huZP2
Transgene:	Tg(ZP2*)4Dean  Location: unknown
Alliance:	Tg(ZP2*)4Dean page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(ZP2*)4Dean expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human ZP2 (7783) Zp2  (MGI:99214)   Mutation details: The full length sequence of the human ZP2 gene in BAC RP11-1023A8 is modified by replacing the corresponding mouse exons encoding amino acids 18-156 (bp 1 in exon 2 to bp 150 in exon 5) for the human amino acids 22-161 (bp 1 in exon 2 to bp 152 in exon 5) at the N-terminus of gene. (J:215794)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:215794 Avella MA, et al., A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans. J Cell Biol. 2014 Jun 23;205(6):801-9
All:	1 reference(s)