Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Zp2*)1Dean
Name:	transgene insertion 1, Jurrien Dean
MGI ID:	MGI:5613983
Synonyms:	hu/moZP2
Transgene:	Tg(Zp2*)1Dean  Location: unknown
Alliance:	Tg(Zp2*)1Dean page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Mutation details: The full length sequence of the mouse Zp2 gene in BAC RP23-6513 is modified by replacing the corresponding human exons encoding amino acids 41-68 (bp 26 in exon 2 to bp 21 in exon 6) for the mouse amino acids 37-165 (bp 59 in exon 2 to bp 6 in exon 5) at the N-terminus of gene. (J:215794)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:215794 Avella MA, et al., A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans. J Cell Biol. 2014 Jun 23;205(6):801-9
All:	1 reference(s)