About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:196070 Tochitani S, et al., Immunoreactivity for GABA, GAD65, GAD67 and Bestrophin-1 in the meninges and the choroid plexus: implications for non-neuronal sources for GABA in the developing mouse brain. PLoS One. 2013;8(2):e56901
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5614472
Gene symbol: Gad1
Gene name: glutamate decarboxylase 1
Antibody: Anti-GAD65/67 C20 sc-7513
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The antibody recognizes both Gad1 and Gad2.
Results
Specimen 3 E12.5 rostral: embryonic day 12.5 (more )
Note: As the meninges develop expressing cells appear in a manner with a rostral to caudal and lateral to dorsal gradient.
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted 3_E12.5 rostral Expression was detected in dorsal meninges in the rostral portion of the developing neocortex.
Specimen 3 E12.5 middle: embryonic day 12.5 (more )
Note: As the meninges develop expressing cells appear in a manner with a rostral to caudal and lateral to dorsal gradient.
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted 3_E12.5 middle In the middle region, expression was detected in the lateral region but not the dorsal region of the neocortex.
Specimen 3 E12.5 mid-caudal: embryonic day 12.5 (more )
Note: As the meninges develop expressing cells appear in a manner with a rostral to caudal and lateral to dorsal gradient.
Structure Level Pattern Image Note
TS20: neocortex Absent 3_E12.5 mid-caudal Expressing cells did not reach even the lateral end of the neocortex.
Specimen 3 E14.5 rostral: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon meninges Present Widespread 3_E14.5 rostral Expression covered the entire neocortex at any position along the rostro-caudal axis.
Specimen 3 E14.5 middle: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon meninges Present Widespread 3_E14.5 middle Expression covered the entire neocortex at any position along the rostro-caudal axis.
Specimen 3 E14.5 caudal: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon meninges Present Widespread 3_E14.5 caudal Expression covered the entire neocortex at any position along the rostro-caudal axis.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory