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Gene Expression Data
Assay Details
Assay
Reference: J:19768 Schofield JN, et al., Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines. Hum Mol Genet. 1994 Aug;3(8):1309-16
Assay type: RNA in situ
MGI Accession ID: MGI:5613510
Gene symbol: Dmd
Gene name: dystrophin, muscular dystrophy
Probe: Ap1-227
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: The probe used in this assay recognizes transcripts in addition to apo-dystrophin-1, but it does not recognize all dystrophin transcripts. It does include exon 63 sequence.
Results
Specimen 2A: embryonic day 11.5 (more )
Note: frontal section
Structure Level Pattern Image Note
TS20: hindbrain floor plate Present 2A
Specimen 2B: embryonic day 12.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS20: spinal cord floor plate Present 2B Expression is present along the entire length.
Specimen 3A: embryonic day 12.5 (more )
Note: frontal section
Structure Level Pattern Image Note
TS20: mandibular process mesenchyme Present Regionally restricted 3A Expression is present in the primordia of future teeth.
TS20: maxillary process mesenchyme Present Regionally restricted 3A Expression is present in the primordia of future teeth.
TS20: floor plate Present 3A ASK FOR BRAIN?
Specimen 4A: embryonic day 12.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: gonad Present 4A
TS20: intestine mesenchyme Present 4A Expression present in intestinal mucosa.
TS20: metanephros Present 4A
TS20: lobar bronchus Present 4A Expression present in developing bronchi of the lung.
Specimen 5B: embryonic day 15.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS23: tooth Present 5B
TS23: vibrissa follicle Present 5B
Specimen 5C: embryonic day 15.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS23: lung Present 5C
TS23: blood vessel Present 5C Expression present in walls of major blood vessels.
TS23: thyroid gland Present 5C
TS23: pancreas Present 5C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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