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Gene Expression Data
Assay Details
Assay
Reference: J:36355 Lowin B, et al., Expression of the CTL-associated protein TIA-1 during murine embryogenesis. J Immunol. 1996 Aug 15;157(4):1448-54
Assay type: RNA in situ
MGI Accession ID: MGI:5613382
Gene symbol: Tia1
Gene name: cytotoxic granule-associated RNA binding protein 1
Probe: Tia1 cDNA4
Probe preparation: Antisense labelled with tritium (H3) RNA
Visualized with: Autoradiography
Results
Specimen Table 1 14.5-day: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Moderate
TS22: brain ventricular layer Moderate
TS22: spinal cord Moderate
TS22: neural retinal epithelium Moderate Regionally restricted Expression was detected in photoreceptor layers of the eye.
TS22: bronchus epithelium Weak
TS22: intestine epithelium Weak
TS22: lung mesenchyme Weak
TS22: olfactory epithelium Weak
TS22: stomach epithelium Weak
TS22: thymus primordium Weak
TS22: inner ear epithelium Weak Expression was weak in otic epithelium.
TS22: lens epithelium Weak Regionally restricted Expression was weak in proliferative lens epithelium.
TS22: bone Absent
TS22: cardiovascular system endothelium Absent
TS22: choroid plexus Absent
TS22: hematopoietic system Absent
TS22: pancreatic acinus Absent
TS22: pancreatic duct Absent
TS22: pigmented retinal epithelium Absent
TS22: salivary gland Absent
TS22: skeletal muscle Absent
TS22: liver parenchyma Absent Expression was not detectable in hepatocytes.

Specimen Table 1 16.5-day: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brain Strong
TS24: spinal cord Strong
TS24: neural retina Strong Regionally restricted Expression was detected in photoreceptor layers of the eye.
TS24: brain ventricular layer Moderate
TS24: bronchus epithelium Moderate
TS24: lung mesenchyme Moderate
TS24: mesenchyme of metanephros Moderate
TS24: olfactory epithelium Moderate
TS24: thymus Moderate
TS24: inner ear epithelium Moderate Expression was detected in otic epithelium.
TS24: lens epithelium Moderate Regionally restricted Expression was detected in proliferative lens epithelium.
TS24: adrenal gland Weak
TS24: intestine epithelium Weak
TS24: salivary gland Weak
TS24: stomach epithelium Weak
TS24: ventricle cardiac muscle Weak
TS24: bone Absent
TS24: cardiovascular system endothelium Absent
TS24: choroid plexus Absent
TS24: hematopoietic system Absent
TS24: pancreatic acinus Absent
TS24: pancreatic duct Absent
TS24: pigmented retinal epithelium Absent
TS24: skeletal muscle Absent
TS24: spleen Absent
TS24: renal tubule Absent Expression was not detectable in kidney tubular epithelium.
TS24: liver and biliary system epithelium Absent Expression was not detectable in biliary epithelium.
TS24: liver parenchyma Absent Expression was not detectable in hepatocytes.

Specimen Table 1 18.5-day: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain Moderate
TS26: brain ventricular layer Moderate
TS26: mesenchyme of metanephros Moderate
TS26: spinal cord Moderate
TS26: neural retina Moderate Regionally restricted Expression was detected in photoreceptor layers of the eye.
TS26: adrenal gland Weak
TS26: bronchus epithelium Weak
TS26: intestine epithelium Weak
TS26: olfactory epithelium Weak
TS26: salivary gland Weak
TS26: stomach epithelium Weak
TS26: thymus Weak
TS26: ventricle cardiac muscle Weak
TS26: inner ear epithelium Weak Weak expression was detected in otic epithelium.
TS26: lens epithelium Weak Regionally restricted Expression was weak in proliferative lens epithelium.
TS26: bone Absent
TS26: cardiovascular system endothelium Absent
TS26: choroid plexus Absent
TS26: hematopoietic system Absent
TS26: lung mesenchyme Absent
TS26: pancreatic acinus Absent
TS26: pancreatic duct Absent
TS26: pigmented retinal epithelium Absent
TS26: skeletal muscle Absent
TS26: spleen Absent
TS26: renal tubule Absent Expression was not detectable in kidney tubular epithelium.
TS26: liver and biliary system epithelium Absent Exression was not detectable in biliary epithelium.
TS26: liver parenchyma Absent Expression was not detectable in hepatocytes.

Specimen 4A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: telencephalon marginal layer Present 4A/B Expression was detected in the neuronal cell layers extending from the ventricular neuroepithelium to the more differentiated cells of the marginal zone.
TS24: telencephalon ventricular layer Present 4A/B Expression was detected in the neuronal cell layers extending from the ventricular neuroepithelium to the more differentiated cells of the marginal zone.
TS24: lateral ventricle choroid plexus Absent 4A/B

Specimen 4C/D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: telencephalon marginal layer Present 4C/D Expression was detected in the neuronal cell layers extending from the ventricular neuroepithelium to the more differentiated cells of the marginal zone.
TS24: telencephalon ventricular layer Present 4C/D Expression was detected in the neuronal cell layers extending from the ventricular neuroepithelium to the more differentiated cells of the marginal zone.
TS24: lateral ventricle choroid plexus Absent 4C/D

Specimen 4G/H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thymus Strong 4G/H

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: bronchus epithelium Strong
TS24: lung mesenchyme Strong

Specimen 6A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: neural retina Strong Regionally restricted 6A/B Expression was abundant in the photoreceptor layers in the retina.

Specimen 7A/B,C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Present Regionally restricted 7A/B , 7C Expression was detected in a subpopulation of neuronal cells in the ventral and dorsal region of the spinal cord.

Specimen 8B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Present 8B

Specimen 9A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: early nephron Strong 9A/B
TS24: mesenchyme of metanephros Strong 9A/B

Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Expression levels were lower at E18.5.
TS26: retina Present Expression levels were lower at E18.5.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory