Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hrastm1Rak
Name:	Harvey rat sarcoma virus oncogene; targeted mutation 1, Raju Kucherlapati
MGI ID:	MGI:5608504
Synonyms:	GV, HarasG12V
Gene:	Hras  Location: Chr7:140770839-140773938 bp, - strand  Genetic Position: Chr7, 86.48 cM
Alliance:	Hrastm1Rak page

Germline Transmission:	Earliest citation of germline transmission: J:94077
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutations:    Insertion, Nucleotide substitutions   Mutation details: The targeting vector contains a loxP-flanked neomycin cassette upstream of a modified exon 2, which contains a G12V mutation with a unique restriction site. The mutation results in a glycine to valine change at position 12. (J:94077)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hras Mutation:	30 strains or lines available

Original:	J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:	1 reference(s)