Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Arc-cre/ERT2)MRhn
Name:	transgene insertion M, Rene Hen
MGI ID:	MGI:5607252
Synonyms:	ArcCreERT2
Transgene:	Tg(Arc-cre/ERT2)MRhn  Location: unknown
Alliance:	Tg(Arc-cre/ERT2)MRhn page

Strain of Origin:

C57BL/6J x CBA

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Arc-cre/ERT2)MRhn expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Arc (MGI:88067)   Mutation details: Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-429N15) containing the entire mouse activity regulated cytoskeletal-associated protein (Arc) gene. A CreERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand-binding domain), followed by an SV40 polyadenylation sequence, was inserted into the translation initiation site of the gene. Founder lines M and F were established and maintained. (J:215456)

Activity:	Tissue activity of this recombinase allele
Driver:	Arc (mouse) Summary of all recombinase alleles driven by Arc. Comparative matrix view of recombinase activities Alliance mouse Arc gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:215456 Denny CA, et al., Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis. Neuron. 2014 Jul 2;83(1):189-201
All:	10 reference(s)