Tg(PRL)30Greg
Transgene Detail
|
|
| Symbol: |
Tg(PRL)30Greg |
| Name: |
transgene insertion 30, Karen Gregerson |
| MGI ID: |
MGI:5604903 |
| Transgene: |
Tg(PRL)30Greg Location: unknown
|
| Alliance: |
Tg(PRL)30Greg page
|
|
| Strain of Origin: |
C57BL/6J x DBA/2
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(PRL)30Greg expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
PRL (5617) |
|
|
|
| |
|
Mutation details: The bacterial artificial chromosome (BAC) RP11273G3 from the Childrens Hospital Oakland Research Institute contains the entire human PRL gene, including the pituitary and extrapituitarypromoters as well as 115 kbp upstream and 38 kbp downstream of the gene-encoding sequences. Purified DNA was used for pronuclear microinjection into fertilized C57Bl/6J X DBA2 hybrid mouse oocytes. Two founder lines were produced (BAC-h8 and BAC-h30).
(J:204079)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:204079 Christensen HR, et al., Completely humanizing prolactin rescues infertility in prolactin knockout mice and leads to human prolactin expression in extrapituitary mouse tissues. Endocrinology. 2013 Dec;154(12):4777-89 |
| All: |
2 reference(s) |
|
Analysis Tools
