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Tg(Actb-Mdm4)6Glo
Transgene Detail
Summary
Symbol: Tg(Actb-Mdm4)6Glo
Name: transgene insertion 6, Guillermina Lozano
MGI ID: MGI:5604361
Synonyms: Mdm4Tg6, Tg6
Transgene: Tg(Actb-Mdm4)6Glo  Location: unknown  
Alliance: Tg(Actb-Mdm4)6Glo page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Actb-Mdm4)6Glo expresses 1 gene
 
Mutation detailsThis transgene is driven by the cytomegalovirus (CMV) immediate-early (IE) enhancer, and the chicken beta actin promoter with an intron that drives widespread expression of an Mdm4 cDNA followed by an SV40 poly(A) sequence. In addition to line 6, line 15 was also created. (J:164225)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Actb-Mdm4)6Glo
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:164225 Xiong S, et al., Spontaneous tumorigenesis in mice overexpressing the p53-negative regulator Mdm4. Cancer Res. 2010 Sep 15;70(18):7148-54
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory