Tg(Actb-EGFP,-Mdm4,-lacZ)1Glo
Transgene Detail
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| Symbol: |
Tg(Actb-EGFP,-Mdm4,-lacZ)1Glo |
| Name: |
transgene insertion 1, Guillermina Lozano |
| MGI ID: |
MGI:5604359 |
| Synonyms: |
Mdm4Tg, Tg |
| Transgene: |
Tg(Actb-EGFP,-Mdm4,-lacZ)1Glo Location: unknown
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| Alliance: |
Tg(Actb-EGFP,-Mdm4,-lacZ)1Glo page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Tg(Actb-EGFP,-Mdm4,-lacZ)1Glo expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Mdm4 (MGI:107934) |
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Mutation details: This transgene is driven by the cytomegalovirus (CMV) immediate-early (IE) enhancer, and the chicken beta actin promoter with an intron that drives widespread expression of an EGFP gene flanked by loxP sites followed by the Mdm4 cDNA, an internal ribosomal entry site (IRES), the lacZ gene, and an SV40 poly(A) sequence. In the absence of cre recombination, EGFP and lacZ are expressed.
(J:164225)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:164225 Xiong S, et al., Spontaneous tumorigenesis in mice overexpressing the p53-negative regulator Mdm4. Cancer Res. 2010 Sep 15;70(18):7148-54 |
| All: |
1 reference(s) |
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Analysis Tools
