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Gene Expression Data
Assay Details
Assay
Reference: J:211539 Chen Y, et al., Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21
Assay type: RNA in situ
MGI Accession ID: MGI:5603303
Gene symbol: Bglap2
Gene name: bone gamma-carboxyglutamate protein 2
Probe: osteocalcin probe6
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Probe specificity was not detailed but may recognize either or both of the related genes Bglap1 (MGI:88156) or Bglap2 (MGI:88157).
Results
Specimen S5M: embryonic day 16.5; Snai1tm2Grid/Snai1tm2Grid (more )
Note: littermate controls carry the floxed allele
Structure Level Pattern Image Note
TS24: femur Present S5M Expression is present in osteoblasts.
Specimen S5N: embryonic day 16.5; Snai1tm1Grid/Snai1tm1Grid, Snai2tm1Grid/Snai2tm1Grid, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: femur Present Regionally restricted S5N Expression levels are delayed and reduced in the double mutant relative to controls, but the pattern of expression is unaltered.
Specimen S5I: embryonic day 18.0; Snai1tm2Grid/Snai1tm2Grid (more )
Note: littermate controls carry the floxed allele
Structure Level Pattern Image Note
TS26: femur Present Regionally restricted S5I Expression is present in osteoblasts.
Specimen S5J: embryonic day 18.0; Snai1tm1Grid/Snai1tm1Grid, Snai2tm1Grid/Snai2tm1Grid, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: femur Present Regionally restricted S5J Expression levels are delayed and reduced in the double mutant relative to controls, but the pattern of expression is unaltered.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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