Acan RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:211539 Chen Y, et al., Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21
Assay type:	RNA in situ
MGI Accession ID:	MGI:5603172
Gene symbol:	Acan
Gene name:	aggrecan

Probe:	Acan probe
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen 6K: embryonic day 16.5; Snai1^tm2Grid/Snai1^tm2Grid (more

)
Note: littermate controls carry the floxed allele

Structure	Level	Pattern	Image	Note
TS24: femur	Present	Regionally restricted	6K	Expression is present in proliferating chondrocytes in the growth plate.

Specimen 6L: embryonic day 16.5; Snai1^tm1Grid/Snai1^tm1Grid, Snai2^tm1Grid/Snai2^tm1Grid, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: femur	Present	Regionally restricted	6L	In the double mutant expression is no longer restricted to the proliferating chondrocytes in the growth plate; it is also detected in the hypertrophic chondrocytes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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