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Gene Expression Data
Assay Details
Assay
Reference: J:185606 Simrick S, et al., Biallelic expression of Tbx1 protects the embryo from developmental defects caused by increased receptor tyrosine kinase signaling. Dev Dyn. 2012 Aug;241(8):1310-24
Assay type: RT-PCR
MGI Accession ID: MGI:5586975
Gene symbol: Spry4
Gene name: sprouty RTK signaling antagonist 4
Probe: Spry4-pC, Spry4-pD
Assay notes: Quantitative RT-PCR assay shown as a graph. Expression is shown relative to Spry1;Spry2 double knock-out expression normalized to Gapdh.
Results
Image: 8G Spry4 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Spry1-/-;Spry2-/- E9.5 TS15: branchial arch Present 0.2 µg; total RNA involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ Spry1tm1.1Jdli/Spry1tm1.1Jdli, Spry2tm1.1Mrt/Spry2tm1.1MrtNot Specified 21-23 somites.
Spry1-/-;Spry2-/-;Tbx1+/- E9.5 TS15: branchial arch Present (a) 0.2 µg; total RNA involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL Spry1tm1.1Jdli/Spry1tm1.1Jdli, Spry2tm1.1Mrt/Spry2tm1.1Mrt, Tbx1tm2.2Bem/Tbx1+Not Specified 21-23 somites.
Notes:
(a) Expression is upregulated in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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