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Tg(CRH-MAPT/Topaz)1Rck
Transgene Detail
Summary
Symbol: Tg(CRH-MAPT/Topaz)1Rck
Name: transgene insertion 1, J M Friedman
MGI ID: MGI:5586654
Synonyms: CRH-GFP
Transgene: Tg(CRH-MAPT/Topaz)1Rck  Location: unknown  
Alliance: Tg(CRH-MAPT/Topaz)1Rck page
Transgene
origin
Strain of Origin:  (CBA x C57BL/6)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA Tau(MAPT)-Topaz/GFP fusion gene with flanking human CRH gene sequences was inserted into the ATG site of the human CRH BAC (397J12) through homologous recombination. Four founder lines were generated; the line with highest GFP expression was characterized. (J:158316)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:158316 Alon T, et al., Transgenic mice expressing green fluorescent protein under the control of the corticotropin-releasing hormone promoter. Endocrinology. 2009 Dec;150(12):5626-32
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory