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Gene Expression Data
Assay Details
Assay
Reference: J:181269 Hong M, et al., Neogenin regulates sonic hedgehog pathway activity during digit patterning. Dev Dyn. 2012 Mar;241(3):627-37
Assay type: RNA in situ
MGI Accession ID: MGI:5586506
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe100
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2C Control: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 2C Shh Control
Specimen 2C Neo1Gt/Gt: embryonic day 11.5; Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 2C Shh Neo1Gt/Gt Expression in this mutant is the same as in wild-type embryos.
Specimen 4 Wt: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Wt
TS19: hindlimb bud Present 4_Shh Wt
Specimen 4 Gli3Xt/+;Neo1+/+: embryonic day 11.5; Gli3Xt-J/Gli3+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/+;Neo1+/+
TS19: hindlimb bud Present 4_Shh Gli3Xt/+;Neo1+/+
Specimen 4 Gli3Xt/Xt;Neo1+/+: embryonic day 11.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/Xt;Neo1+/+ There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.
TS19: hindlimb bud Present 4_Shh Gli3Xt/Xt;Neo1+/+ There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.
Specimen 4 Gli3+/+;Neo1Gt/Gt: embryonic day 11.5; Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3+/+;Neo1Gt/Gt
TS19: hindlimb bud Present 4_Shh Gli3+/+;Neo1Gt/Gt
Specimen 4 Gli3Xt/+;Neo1Gt/Gt: embryonic day 11.5; Gli3Xt-J/Gli3+, Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/+;Neo1Gt/Gt Expression in this mutant is the same as in wild-type embryos.
TS19: hindlimb bud Present 4_Shh Gli3Xt/+;Neo1Gt/Gt Expression in this mutant is the same as in wild-type embryos.
Specimen 4 Gli3Xt/Xt;Neo1Gt/Gt: embryonic day 11.5; Gli3Xt-J/Gli3Xt-J, Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/Xt;Neo1Gt/Gt There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.
TS19: hindlimb bud Present 4_Shh Gli3Xt/Xt;Neo1Gt/Gt There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory