About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:181269 Hong M, et al., Neogenin regulates sonic hedgehog pathway activity during digit patterning. Dev Dyn. 2012 Mar;241(3):627-37
Assay type: RNA in situ
MGI Accession ID: MGI:5586506
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe100
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2C Control: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 2C Shh Control

Specimen 2C Neo1Gt/Gt: embryonic day 11.5; Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 2C Shh Neo1Gt/Gt Expression in this mutant is the same as in wild-type embryos.

Specimen 4 Wt: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Wt
TS19: hindlimb bud Present 4_Shh Wt

Specimen 4 Gli3Xt/+;Neo1+/+: embryonic day 11.5; Gli3Xt-J/Gli3+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/+;Neo1+/+
TS19: hindlimb bud Present 4_Shh Gli3Xt/+;Neo1+/+

Specimen 4 Gli3Xt/Xt;Neo1+/+: embryonic day 11.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/Xt;Neo1+/+ There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.
TS19: hindlimb bud Present 4_Shh Gli3Xt/Xt;Neo1+/+ There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.

Specimen 4 Gli3+/+;Neo1Gt/Gt: embryonic day 11.5; Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3+/+;Neo1Gt/Gt
TS19: hindlimb bud Present 4_Shh Gli3+/+;Neo1Gt/Gt

Specimen 4 Gli3Xt/+;Neo1Gt/Gt: embryonic day 11.5; Gli3Xt-J/Gli3+, Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/+;Neo1Gt/Gt Expression in this mutant is the same as in wild-type embryos.
TS19: hindlimb bud Present 4_Shh Gli3Xt/+;Neo1Gt/Gt Expression in this mutant is the same as in wild-type embryos.

Specimen 4 Gli3Xt/Xt;Neo1Gt/Gt: embryonic day 11.5; Gli3Xt-J/Gli3Xt-J, Neo1Gt(KST265)Byg/Neo1Gt(KST265)Byg (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 4_Shh Gli3Xt/Xt;Neo1Gt/Gt There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.
TS19: hindlimb bud Present 4_Shh Gli3Xt/Xt;Neo1Gt/Gt There is a ectopic anterior domain of expression in this mutant in both fore- and hindlimbs.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/28/2024
MGI 6.13
The Jackson Laboratory