Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mir22tm1.1Dzw
Name:	microRNA 22; targeted mutation 1.1, Da-Zhi Wang
MGI ID:	MGI:5585448
Synonyms:	miR-22flox
Gene:	Mir22  Location: Chr11:75354542-75354636 bp, + strand  Genetic Position: Chr11, 45.91 cM
Alliance:	Mir22tm1.1Dzw page

Germline Transmission:	Earliest citation of germline transmission: J:213308
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: Exon 2 was flanked by loxP sites and a positive-selection neomycin cassette flanked by FRT sites was inserted downstream of exon 2. The neomycin cassette was excised by FLP-mediated recombination. (J:213308)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir22 Mutation:	6 strains or lines available

Original:	J:213308 Huang ZP, et al., MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circ Res. 2013 Apr 26;112(9):1234-43
All:	1 reference(s)